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Antigenic Specificity | PMCA1 ATPase |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, porcine, rat |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | ELISA: Assay dependent, Immunohistochemistry (Frozen): 1:20, Immunohistochemistry (Paraffin): 1:20, Western Blot: 1:1,000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PMCA1 ATPase Polyclonal Antibody. The calcium pump of the plasma membrane, termed PMCA ATPase, pumps calcium from the cytosol to the extracellular space. This membrane-bound enzyme is related to a number of other ATPases including the SERCA ATPase and the sodium/potassium pump. There are four different genes encoding PMCA ATPase and studies have revealed 20 isoforms of the pump generated by alternate splicing of the primary gene products. mRNA distribution studies show that gene products 1 and 4 are transcribed in most tissues, however, products 2 and 3 are more tissue specific. Transcription of the splicing variants has also been found to be tissue specific. In the pancreas, where insulin secretion is calcium dependent, the beta cells only |
Immunogen | n/a |
Other Names | Plasma Membrane Calcium Pump ATPase 1 |
Gene, Accession # | Entrez: 29598, 397636, 490; Uniprot: P11505, P20020, P23220 |
Catalog # | PA1-914 |
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Order / More Info | PMCA1 ATPase Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 14507885, 16249176, 16855061, 18322081, 18334228, 20553254, 22137721, 24439526, 26274509, 27813079, 28596940 |
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