产品详情 |
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Antigenic Specificity | IL-5 |
Clone | TRFK5 |
Host Species | Rat |
Reactive Species | human, mouse |
Isotype | IgG1, kappa |
Format | purified |
Size | 500 µg |
Concentration | n/a |
Applications | ELISA: 1-4 µg/mL, Flow Cytometry: Assay-Dependent, Functional Assay: Assay-Dependent, Neutralization: Assay-Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IL-5 Monoclonal Antibody (TRFK5), eBioscience™. IL-5 is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. IL-5 cytokine is a main regulator of eosinopoiesis, eosinophil maturation and activation. The elevated production of this cytokine is reported to be related to asthma or hypereosinophilic syndromes. The receptor of IL-5 cytokine is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). IL-5, together with those for interleukin 4 (IL4), interleukin 13 (IL13), and CSF2, form a cytokine gene cluster on chromosome 5. IL-5, IL4, and IL13 are found to be regulated coordinately by long-range regulatory elements spre |
Immunogen | n/a |
Other Names | Interleukin-5, EDF, IL-5, TRF, T-cell replacing factor, TRF, Eosinophil differentiation factor, B cell differentiation factor I |
Gene, Accession # | Entrez: 16191, 3567; Uniprot: P04401, P05113 |
Catalog # | 14-7052-85 |
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Order / More Info | IL-5 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 17601518, 18094193, 19234154, 23032791, 24068930, 24958709, 25816012, 26339310, 27621809 |
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