产品详情 |
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Antigenic Specificity | Bassoon |
Clone | SAP7F407 |
Host Species | Mouse |
Reactive Species | mouse, rat |
Isotype | IgG2a |
Format | purified |
Size | 50 µg |
Concentration | n/a |
Applications | Immunocytochemistry: 0.5-5 µg/mL, Immunofluorescence: Assay-dependent, Immunohistochemistry: 2 µg/mL, Immunoprecipitation: Assay dependent, Western Blot: 1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Bassoon Monoclonal Antibody (SAP7F407). Bassoon is a ~420 kDa protein that is a localized at the presynaptic nerve terminals and is believed to play a role in the structural and functional organization of the synaptic vesicle cycle. Bassoon does not belong to any known protein families. It has been found in rat and mouse with sequence identity of the two proteins at 96%. The human BASSOON gene has recently been cloned and localized. Bassoon is predicted to contain two double-zinc fingers, three coiled-coil regions, and two polyglutamine domains. The polyglutamine domains in the C-terminus are of interest, since it is known that for some human proteins, such as Huntingtin, abnormal amplification of this region can cause late-onset neurodegen |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | Entrez: 12217, 29138; Uniprot: O88737, O88778 |
Catalog # | MA1-20689 |
Price | |
Order / More Info | Bassoon Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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