| 产品详情 |
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| Antigenic Specificity | Bax |
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| Clone | 2D2 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, nonhuman primate |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | ELISA: Assay Dependent, Immunohistochemistry (Paraffin): 1:50-1:500, Immunoprecipitation: Assay Dependent, Western Blot: 1:100 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Bax Monoclonal Antibody (2D2). BAX is a members of the Bcl-2 Family and plays an important role in regulation of apoptosis. Whereas Bcl-2 is commonly regarded as an anti-apoptotic protein, BAX is considered to have a pro-apoptotic function. Regulation of apoptosis is supposed to involve both homo- and heterodimerization of different isoforms of BAX and Bcl-2. The Bax gene encodes different isoforms including Bax alpha (21 kDa) and Bax beta (24 kDa), whereas both isoforms contain the BH1, BH2 and BH3 domains, Bax beta has a unique carboxyl terminus and does not contain a hydrophobic transmembrane domain. Bcl-2 is also expressed in different Isoforms. Bcl-2 beta differs in the 3' UTR and coding region compared to variant alpha. Bcl-2 beta is |
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| Immunogen | n/a |
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| Other Names | Bcl-2-like protein 4, Bcl2-L-4, BAX, BCL2L4 |
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| Gene, Accession # | Entrez: 12028, 581; Uniprot: Q07812, Q07813 |
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| Catalog # | 33-6400 |
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| Price | |
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| Order / More Info | Bax Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 11839668, 11880365, 11895913, 12180228, 12637494, 12754745, 12805322, 14987230, 15005691, 16200460, 16679870, 21566207, 22179774, 23481040, 26794447, 27832139, 9973477 |
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