| 产品详情 |
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| Antigenic Specificity | Bax |
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| Clone | 2D2 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1, kappa |
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| Format | biotin conjugate |
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| Size | 500 µL |
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| Concentration | n/a |
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| Applications | Immunofluorescence: Assay Dependent, Immunohistochemistry (Paraffin): 2-4 µg/mL, Western Blot: 1 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Bax Monoclonal Antibody (2D2), Biotin. BAX is a members of the Bcl-2 Family and plays an important role in regulation of apoptosis. Whereas Bcl-2 is commonly regarded as an anti-apoptotic protein, BAX is considered to have a pro-apoptotic function. Regulation of apoptosis is supposed to involve both homo- and heterodimerization of different isoforms of BAX and Bcl-2. The Bax gene encodes different isoforms including Bax alpha (21 kDa) and Bax beta (24 kDa), whereas both isoforms contain the BH1, BH2 and BH3 domains, Bax beta has a unique carboxyl terminus and does not contain a hydrophobic transmembrane domain. Bcl-2 is also expressed in different Isoforms. Bcl-2 beta differs in the 3' UTR and coding region compared to variant alpha. Bcl-2 |
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| Immunogen | n/a |
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| Other Names | apoptosis regulator BAX, bcl-2-like protein 4, bcl2-L-4 |
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| Gene, Accession # | Entrez: 581; Uniprot: Q07812 |
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| Catalog # | MA5-13991 |
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| Price | |
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| Order / More Info | Bax Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 11690683, 12010367, 12076274, 12165421, 12372606, 14694160, 15005691, 15161684, 15168338, 15797072, 16043260, 16086078, 16151650, 16203276, 16253767, 16445949, 16481065, 16546135, 16839211, 17096185, 17534116, 18035936, 18261626, 18528276, 18843185, 19013426, 19336448, 19729672, 20025478, 20048747, 20126473, 20214740, 21442622, 22121263, 22198862, 22339673, 22397815, 22661399, 22995373, 23192275, 23319010, 23418433 |
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