| 产品详情 |
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| Antigenic Specificity | Bax |
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| Clone | 6A7 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, nonhuman primate, rat |
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| Isotype | IgG1, kappa |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blot: 1 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Bax Monoclonal Antibody (6A7), eBioscience™. BAX is a members of the Bcl-2 Family and plays an important role in regulation of apoptosis. Whereas Bcl-2 is commonly regarded as an anti-apoptotic protein, BAX is considered to have a pro-apoptotic function. Regulation of apoptosis is supposed to involve both homo- and heterodimerization of different isoforms of BAX and Bcl-2. The Bax gene encodes different isoforms including Bax alpha (21 kDa) and Bax beta (24 kDa), whereas both isoforms contain the BH1, BH2 and BH3 domains, Bax beta has a unique carboxyl terminus and does not contain a hydrophobic transmembrane domain. Bcl-2 is also expressed in different Isoforms. Bcl-2 beta differs in the 3' UTR and coding region compared to variant a |
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| Immunogen | n/a |
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| Other Names | BCL2L4 |
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| Gene, Accession # | Entrez: 12028, 24887, 581; Uniprot: Q07812, Q07813, Q63690 |
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| Catalog # | 14-6997-82 |
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| Price | |
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| Order / More Info | Bax Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 15545281, 17102131, 17452332, 20353948, 21475200, 21951169, 22308310 |
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