| 产品详情 |
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| Antigenic Specificity | Bax |
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| Clone | 6A7 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 500 µL |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 0.5 µg/test, Immunocytochemistry: 1:10-1:100, Immunofluorescence: 1:10-1:100, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:10-1:100 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Bax Monoclonal Antibody (6A7). BAX is a members of the Bcl-2 Family and plays an important role in regulation of apoptosis. Whereas Bcl-2 is commonly regarded as an anti-apoptotic protein, BAX is considered to have a pro-apoptotic function. Regulation of apoptosis is supposed to involve both homo- and heterodimerization of different isoforms of BAX and Bcl-2. The Bax gene encodes different isoforms including Bax alpha (21 kDa) and Bax beta (24 kDa), whereas both isoforms contain the BH1, BH2 and BH3 domains, Bax beta has a unique carboxyl terminus and does not contain a hydrophobic transmembrane domain. Bcl-2 is also expressed in different Isoforms. Bcl-2 beta differs in the 3' UTR and coding region compared to variant alpha. Bcl-2 beta is |
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| Immunogen | n/a |
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| Other Names | apoptosis regulator BAX, bcl-2-like protein 4, bcl2-L-4 |
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| Gene, Accession # | Entrez: 12028, 24887, 581; Uniprot: Q07812, Q07813, Q63690 |
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| Catalog # | MA5-14003 |
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| Price | |
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| Order / More Info | Bax Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 15665397, 17010314, 17457759, 17519046, 17904098, 18021195, 18187175, 19481559, 19665148, 20339081, 20627562, 21067863, 21107704, 22096592, 22128883, 22282242, 25191525, 25860257, 29148970 |
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