| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | Bax |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human, mouse |
|---|
| Isotype | n/a |
|---|
| Format | purified |
|---|
| Size | 400 µL |
|---|
| Concentration | n/a |
|---|
| Applications | Flow Cytometry: 1:25, Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:2000 |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Bax Polyclonal Antibody. BAX is a members of the Bcl-2 Family and plays an important role in regulation of apoptosis. Whereas Bcl-2 is commonly regarded as an anti-apoptotic protein, BAX is considered to have a pro-apoptotic function. Regulation of apoptosis is supposed to involve both homo- and heterodimerization of different isoforms of BAX and Bcl-2. The Bax gene encodes different isoforms including Bax alpha (21 kDa) and Bax beta (24 kDa), whereas both isoforms contain the BH1, BH2 and BH3 domains, Bax beta has a unique carboxyl terminus and does not contain a hydrophobic transmembrane domain. Bcl-2 is also expressed in different Isoforms. Bcl-2 beta differs in the 3' UTR and coding region compared to variant alpha. Bcl-2 beta is shorte |
|---|
| Immunogen | n/a |
|---|
| Other Names | apoptosis regulator BAX |
|---|
| Gene, Accession # | Entrez: 12028, 581; Uniprot: Q07812, Q07813 |
|---|
| Catalog # | PA5-11378 |
|---|
| Price | |
|---|
| Order / More Info | Bax Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | PubMed: 21984918 |
|---|
| 产品资料 |
|
|