产品详情 |
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Antigenic Specificity | LST1 |
Clone | LST1/02 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Immunocytochemistry: Assay dependent, Immunoprecipitation: Assay Dependent, Western Blot: Assay Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | LST1 Monoclonal Antibody (LST1/02). LST1 (leukocyte-specific transcript, also known as B144) is expressed in cells of myeloid/erythroid lineage (monocytes, granulocytes, dendritic cells, platelets, erythrocytes). At least 14 alternatively spliced variants (LST1/A - LST1/N) can be detected; some of them (LST1/A, B, C, G, I, K) are transmembrane cell surface-exposed forms, the other are soluble. LST1 induces production of long, thin filopodia in dendritic cells, has an inhibitory effect on lymphocyte proliferation and may have an immunomodulatory role. LST1/A is an 11 kDa transmembrane adaptor present in membrane rafts and forms spontaneously covalent homodimers. Its intracellular domain contains two tyrosine motifs, one of them being an ITIM |
Immunogen | n/a |
Other Names | DAAP-90L16.2, B144, D6S49E, LST-1, MGC119006, MGC119007, leucocyte specific transcript 1, leukocyte-specific transcript 1 protein, lymphocyte antigen 117 |
Gene, Accession # | Entrez: 7940; Uniprot: O00453 |
Catalog # | MA1-10400 |
Price | |
Order / More Info | LST1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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