| 产品详情 |
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| Antigenic Specificity | DC-SIGN |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 10 µg/mL, Western Blot: 2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | DC-SIGN Polyclonal Antibody. Dendritic cells (DCs) that control immune responses were recently found to capture and transport HIV from the mucosal area to remote lymph nodes, where DCs hand over HIV to CD4+ T lymphocytes. DCs also amplify the amount of virus and extend the duration of viral infectivity. Multiple strains of HIV-1, HIV-2 and SIV bind to DCs via DC-SIGN. ICAM-3 is the natural ligand for DC-SIGN. A DC-SIGN homologue (termed DC-SIGNR, L-SIGN, and DC-SIGN2) was identified recently. DC-SIGN forms a novel gene family with DC-SIGNR and many alternatively spliced isoforms of DC-SIGN and DC-SIGNR. The expression of DC-SIGN was found in mucosal tissues including placenta, small intestine, and rectum. |
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| Immunogen | n/a |
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| Other Names | CDSIGN, CLEC4L, DC-SIGN, DC-SIGN1; C-type lectin domain family 4 member L; C-type lectin domain family 4, member L; CD209 antigen; HIV gpl20-binding protein; dendritic cell-specific ICAM-3-grabbing non-integrin 1; dendritic cell-specific intracellular adhesion molecules (ICAM)-3 grabbing non-integrin |
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| Gene, Accession # | Entrez: 30835; Uniprot: Q9NNX6 |
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| Catalog # | PA5-19967 |
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| Price | |
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| Order / More Info | DC-SIGN Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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