产品详情 |
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Antigenic Specificity | DCTN2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Western Blot: 1:1,000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | DCTN2 Polyclonal Antibody. This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. |
Immunogen | n/a |
Other Names | DCTN50, DYNAMITIN, RBP50, 50 kD dynein-associated polypeptide, 50 kDa dynein-associated polypeptide, dynactin complex 50 kD subunit, dynactin complex 50 kDa subunit, dynactin subunit 2, p50 dynamitin |
Gene, Accession # | Entrez: 10540, 69654; Uniprot: Q13561, Q99KJ8 |
Catalog # | A303-488A-M |
Price | |
Order / More Info | DCTN2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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