| 产品详情 |
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| Antigenic Specificity | DcTRAILR1 |
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| Clone | 270012 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2A |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | lyophilized |
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| Applications | Immunocytochemistry: 8-25 µg/mL, Immunofluorescence: 8-25 µg/mL, Western Blot: 1 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | DcTRAILR1 Monoclonal Antibody (270012). Mouse DcTRAILR1 and DcTRAILR2 (decoy TRAIL receptors 1 and 2) proteins are receptors for TRAIL according to ligand-receptor binding assays (Schneider et al. 2001). However, overexpression does not cause NF-kB activation or apoptosis, as would be expected of a TRAIL receptor. These observations led researchers to refer to these receptors as decoys. It is thought that cells that express decoy TRAIL receptor decoys at high levels relative to actual TRAIL receptors may use decoys as protection against the cytotoxic action of TRAIL (reviewed in Bouralexis et al. 2005). Additional analysis of these two murine TRAIL decoy receptors should help faciliate the understanding of the complex biology underlying TRA |
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| Immunogen | n/a |
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| Other Names | Dctrailr1, MGC123882, MGC123883, Tnfrh1, Tnfrsf1al1, mDcTrailr1, mSOB |
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| Gene, Accession # | Entrez: 79201; Uniprot: Q9ER63 |
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| Catalog # | MA5-23971 |
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| Price | |
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| Order / More Info | DcTRAILR1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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