产品详情 |
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Antigenic Specificity | Rhotekin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunocytochemistry: 1:100-1:1000, Immunofluorescence: 1:100-1:1000, Western Blot: 1:1000-1:10,000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rhotekin Polyclonal Antibody. This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | Entrez: 20166, 6242; Uniprot: Q8C6B2, Q9BST9 |
Catalog # | PA5-29931 |
Price | |
Order / More Info | Rhotekin Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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