| 产品详情 |
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| Antigenic Specificity | MKNK2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | bovine, canine, equine, guinea pig, human, mouse, rabbit, rat, zebrafish |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 5 µg/mL, Western Blot: 1 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MKNK2 Polyclonal Antibody. MAP kinase-interacting kinase 1 (Mnk1) and Mnk2, members of the Ser/Thr protein kinase family, bind tightly to the growth factor-regulated MAP kinases, Erk1 and Erk2. Erk and p38 phosphorylate MNK1 and Mnk2, which stimulates their in vitro kinase activity toward a substrate, eukaryotic initiation factor-4E (eIF-4E). Overexpression of Mnk2 results in increased phosphorylation of endogenous eIF-4E, showing that it can act as an eIF-4E kinase in vivo. Mnk2 may play a role in the response to environmental stress and cytokines. This ubiquitiously expressed protein appears to regulate transcription by phosphorylating eIF-4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap. Expr |
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| Immunogen | n/a |
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| Other Names | MAP kinase interacting serine/threonine kinase 2, GPRK7, MNK2 |
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| Gene, Accession # | Entrez: 100146117, 100734192, 17347, 2872, 299618, 538519, 612212; Uniprot: Q5U2N4, Q8CDB0, Q9HBH9 |
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| Catalog # | PA5-44322 |
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| Price | |
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| Order / More Info | MKNK2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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