产品详情 |
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Antigenic Specificity | MKP2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 400 µL |
Concentration | n/a |
Applications | Immunohistochemistry: 1:50-1:100, Western Blot: 1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | MKP2 Polyclonal Antibody. DUSP4 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP4 inactivates ERK1, ERK2 and JNK, is expressed in a va |
Immunogen | n/a |
Other Names | Mitogen-activated protein kinase phosphatase 2; MAP kinase phosphatase 2; MKP-2; Dual specificity protein phosphatase hVH2; |
Gene, Accession # | Entrez: 1846, 319520; Uniprot: Q13115, Q8BFV3 |
Catalog # | PA5-15549 |
Price | |
Order / More Info | MKP2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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