| 产品详情 |
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| Antigenic Specificity | NSE2 |
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| Clone | OTI4A2 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 1:100, Immunocytochemistry: 1:100, Immunofluorescence: 1:100, Western Blot: 1:500 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | NSE2 Monoclonal Antibody (OTI4A2). MMS21, also known as NSE2, is a SUMO ligase that in combination with the SMC5/6 complex is required for the prevention of DNA damage induced apoptosis by facilitating DNA repair in human cells. MMS21-dependent sumoylation is integral and important to the cohesion mechanism and mitotic progression; this function appears to be independent of SMC6. MMS21 mediates SUMO attachment to various proteins such as SMC6L1 and TRAX, and possibly the cohesin components RAD21 and STAG2. |
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| Immunogen | n/a |
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| Other Names | C8orf36, MMS21, NSE2; E3 SUMO-protein ligase NSE2; MMS21 homolog; hMMS21; methyl methanesulfonate sensitivity gene 21; non-SMC element 2 homolog; non-structural maintenance of chromosomes element 2 homolog |
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| Gene, Accession # | Entrez: 286053; Uniprot: Q96MF7 |
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| Catalog # | MA5-25224 |
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| Price | |
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| Order / More Info | NSE2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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