产品详情 |
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Antigenic Specificity | NSG1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NSG1 Polyclonal Antibody. NEEP21 (neuron-enriched endosomal 21kDa protein), also known as brain neuron cytoplasmic protein 1, NSG1 (neuron-specific proteins family member 1), P21 or D4S234E, is a single pass type II membrane protein belonging to the NSG family. It is highly expressed during neuronal maturation but its expression is downregulated in adult tissues. NEEP21 predominantly localizes to Rab 4-positive early endosomes in the somatodendritic neuronal compartment and is essential for proper receptor sorting and recycling in neurons. It associates with GRIP1 and GluR-2 and mediates the surface expression of GluR-2. When this interaction is interrupted, GluR-2 accumulates in early endosomes and leads to changes in evoked synaptic curre |
Immunogen | n/a |
Other Names | Brain neuron cytoplasmic protein 1, Brain specific mRNA b, Bsmrb, Neuron-specific gene family member 1, Neuron-specific protein family member 1, NSG1, NSG1, PEP1, D4S234E |
Gene, Accession # | Entrez: 18196, 25247, 27065; Uniprot: P02683, P42857, Q62092 |
Catalog # | PA5-36497 |
Price | |
Order / More Info | NSG1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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