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Product Name | Human IL21 Protein (Recombinant) |
Description | Purity >95% by SDS-PAGE, MW: 15.4 kDa. Interleukin 21 (IL-21) is a member of the common-gamma chain family of cytokines that are involved in immunoregulation. IL-21 is normally expressed by activated CD4+ T cells and is aberrantly expressed in Hodgkin lymphoma cells. The IL-21 receptor (IL-21R) activates the JAK/STAT signaling pathway and is expressed on T, B, and natural killer (NK) cells. Within the B cell lineage, IL-21 is a switch factor regulating IgG1 and IgG3 antibody production. IL-21 also cooperates with IL-4 for the production of multiple antibody classes in B cells. IL-21 has pleiotropic effects on the proliferation, differentiation, and effector functions of B, T, NK, and dendritic cells. |
Size | n/a |
Concentration | n/a |
Applications | n/a |
Other Names | IL21, Interleukin 21, Interleukin-21, Interleukin-21 isoform, Za11, IL-21 |
Gene, Accession, CAS # | IL21, Gene ID: 59067 |
Catalog # | LS-G23667 |
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Order / More Info | Human IL21 Protein (Recombinant) from LIFESPAN BIOSCIENCES INC. |
Product Specific References | n/a |
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