| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | Granzyme B |
|---|
| Clone | 496B |
|---|
| Host Species | Rat |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG2a, kappa |
|---|
| Format | purified |
|---|
| Size | 25 µg |
|---|
| Concentration | n/a |
|---|
| Applications | Immunocytochemistry: Assay-Dependent, Immunofluorescence: Assay-Dependent, Immunohistochemistry (Paraffin): 5 µg/mL, Western Blot: 1 µg/mL |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Granzyme B Monoclonal Antibody (496B), eBioscience™. Granzyme B is a member of the granzyme serine protease family, and is found in the granules of cytotoxic T cells and NK cells. Granzyme B has been described as CGL1 (cathepsin G-like-1), a serine protease expressed only in cytotoxic T-lymphocytes after cell activation, and CTLA-1 (cytotoxic T lymphocyte-associated serine esterase 1) based on identification of mRNA in various cytotoxic T cells, but not observed in non-cytotoxic lymphoid cells. Granzyme B is crucial for the rapid induction of target cell death by apoptosis, induced by interaction with cytotoxic T cells. The receptor involved in this process has been identified as mannose 6-phosphate receptor which functions as a death |
|---|
| Immunogen | n/a |
|---|
| Other Names | GrB |
|---|
| Gene, Accession # | Entrez: 3002; Uniprot: P10144 |
|---|
| Catalog # | 14-8889-80 |
|---|
| Price | |
|---|
| Order / More Info | Granzyme B Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|