| 产品详情 |
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| Antigenic Specificity | Granzyme B |
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| Clone | GB11 |
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| Host Species | Mouse |
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| Reactive Species | human, nonhuman primate, rhesus monkey |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | ELISA: 2-5 µg/mL, Flow Cytometry: 1/10 - 1/100, Immunofluorescence: Assay Dependent, Immunohistochemistry (Frozen): Assay Dependent, Immunoprecipitation: Assay Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Granzyme B Monoclonal Antibody (GB11). Granzyme B is a member of the granzyme serine protease family, and is found in the granules of cytotoxic T cells and NK cells. Granzyme B has been described as CGL1 (cathepsin G-like-1), a serine protease expressed only in cytotoxic T-lymphocytes after cell activation, and CTLA-1 (cytotoxic T lymphocyte-associated serine esterase 1) based on identification of mRNA in various cytotoxic T cells, but not observed in non-cytotoxic lymphoid cells. Granzyme B is crucial for the rapid induction of target cell death by apoptosis, induced by interaction with cytotoxic T cells. The receptor involved in this process has been identified as mannose 6-phosphate receptor which functions as a death receptor for Granzy |
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| Immunogen | n/a |
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| Other Names | CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT |
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| Gene, Accession # | Entrez: 3002, 716518; Uniprot: P10144 |
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| Catalog # | MA1-80734 |
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| Price | |
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| Order / More Info | Granzyme B Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 15980149, 16357323, 16365411, 16912282, 17312126, 17569889, 17617575, 18802095, 19103877, 19265125, 19338979, 20038786, 20501837, 20592282, 21441446, 21873525, 21940678, 21978002, 22006977, 22345460, 22406458, 22490682, 22634866, 22885140, 23183896, 23211929, 23536666, 23733882, 24088571, 24452537, 24550909, 24850719, 25043946, 25255454, 25260825, 25348153, 25637022, 26122661, 26220086, 26699642, 26789248, 26999026, 28084312, 28176332 |
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