| 产品详情 |
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| Antigenic Specificity | Granzyme B |
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| Clone | GB12 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | allophycocyanin (APC) conjugate |
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| Size | 500 µL |
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| Concentration | n/a |
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| Applications | Flow Cytometry: Assay Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Granzyme B Monoclonal Antibody (GB12), APC. Granzyme B is a member of the granzyme serine protease family, and is found in the granules of cytotoxic T cells and NK cells. Granzyme B has been described as CGL1 (cathepsin G-like-1), a serine protease expressed only in cytotoxic T-lymphocytes after cell activation, and CTLA-1 (cytotoxic T lymphocyte-associated serine esterase 1) based on identification of mRNA in various cytotoxic T cells, but not observed in non-cytotoxic lymphoid cells. Granzyme B is crucial for the rapid induction of target cell death by apoptosis, induced by interaction with cytotoxic T cells. The receptor involved in this process has been identified as mannose 6-phosphate receptor which functions as a death receptor for G |
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| Immunogen | n/a |
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| Other Names | CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT |
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| Gene, Accession # | Entrez: 3002; Uniprot: P10144 |
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| Catalog # | MHGB05 |
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| Price | |
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| Order / More Info | Granzyme B Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 15238416, 15699103, 15728503, 15840696, 16051854, 16106370, 16113299, 17047079, 17579022, 17728236, 18256155, 18641321, 18768835, 19404988, 19592644, 19671923, 20592284, 20600446, 20618588, 20660788, 20668091, 20702730, 20924102, 20975043, 21131593, 21483446, 21719602, 22236998, 22393401, 22538855, 23836150, 23926350, 24076634, 24554773, 25367158, 25751266, 26161083, 27337592, 27861291, 28300057 |
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