| 产品详情 |
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| Antigenic Specificity | Granzyme B |
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| Clone | GB12 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | phycoerythrin (PE) conjugate |
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| Size | 500 µL |
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| Concentration | n/a |
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| Applications | Flow Cytometry: Assay Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Granzyme B Monoclonal Antibody (GB12), PE. Granzyme B is a member of the granzyme serine protease family, and is found in the granules of cytotoxic T cells and NK cells. Granzyme B has been described as CGL1 (cathepsin G-like-1), a serine protease expressed only in cytotoxic T-lymphocytes after cell activation, and CTLA-1 (cytotoxic T lymphocyte-associated serine esterase 1) based on identification of mRNA in various cytotoxic T cells, but not observed in non-cytotoxic lymphoid cells. Granzyme B is crucial for the rapid induction of target cell death by apoptosis, induced by interaction with cytotoxic T cells. The receptor involved in this process has been identified as mannose 6-phosphate receptor which functions as a death receptor for Gr |
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| Immunogen | n/a |
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| Other Names | CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT |
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| Gene, Accession # | Entrez: 3002; Uniprot: P10144 |
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| Catalog # | MHGB04 |
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| Price | |
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| Order / More Info | Granzyme B Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 12594335, 12816977, 15238416, 15265799, 15470036, 15728503, 15840696, 16139892, 16146542, 16418326, 16611250, 16836648, 17047079, 17301952, 17404276, 17628586, 17996944, 18256155, 18469826, 18495780, 19124743, 19592644, 20339088, 20600446, 20924102, 20975043, 21131593, 21343349, 21684140, 21884408, 21911464, 21939709, 22084442, 22704624, 22894956, 23152535, 23524976, 23746652, 24465991, 24497611, 24680062, 24723371, 24789914, 25113973, 25662997, 27171408, 27707928, 27733554 |
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