| 产品详情 |
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| Antigenic Specificity | Granzyme B |
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| Clone | NGZB |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a, kappa |
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| Format | PE-Cyanine7 conjugate |
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| Size | 25 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 0.125 µg/test |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Granzyme B Monoclonal Antibody (NGZB), PE-Cyanine7, eBioscience™. Granzyme B is a member of the granzyme serine protease family, and is found in the granules of cytotoxic T cells and NK cells. Granzyme B has been described as CGL1 (cathepsin G-like-1), a serine protease expressed only in cytotoxic T-lymphocytes after cell activation, and CTLA-1 (cytotoxic T lymphocyte-associated serine esterase 1) based on identification of mRNA in various cytotoxic T cells, but not observed in non-cytotoxic lymphoid cells. Granzyme B is crucial for the rapid induction of target cell death by apoptosis, induced by interaction with cytotoxic T cells. The receptor involved in this process has been identified as mannose 6-phosphate receptor which functio |
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| Immunogen | n/a |
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| Other Names | GrB |
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| Gene, Accession # | Entrez: 14939; Uniprot: P04187 |
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| Catalog # | 25-8898-80 |
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| Price | |
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| Order / More Info | Granzyme B Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 23733873, 25156726, 25261477, 25337993, 25348003, 25995257, 26456581, 26467188, 28123877, 28382040, 28504276, 29150606, 29403003 |
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