产品详情 |
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Antigenic Specificity | Granzyme K |
Clone | G3H69 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a, kappa |
Format | PerCP-eFluor 710 conjugate |
Size | 100 Tests |
Concentration | n/a |
Applications | Flow Cytometry: 5 µL (0.03 µg)/test |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Granzyme K Monoclonal Antibody (G3H69), PerCP-eFluor 710, eBioscience™. Granzyme K (GrK) belongs to a family of trypsin-like serine proteases localised in the cytotoxic granules of activated T cells and NK cells. It encodes a 28 kDa serine protease whose gene is located on chromosome 5q11-12 close to the granzyme A-encoding gene. Like granzyme A, it has a trypsin-like specifity cleaving at the basic residues arginine and lysine. Granzyme K triggers rapid cell death independently of caspase activation with single-stranded DNA nicks and is primarily expressed in thymus, lung, spleen and peripheral blood leukocytes. |
Immunogen | n/a |
Other Names | GrK |
Gene, Accession # | Entrez: 3003; Uniprot: P49863 |
Catalog # | 46-8897-42 |
Price | |
Order / More Info | Granzyme K Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 25609800 |
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