产品详情 |
Edit |   |
Antigenic Specificity | Granzyme K |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | ELISA: 1:20,000, Immunocytochemistry: 1:200-1:1000, Immunofluorescence: 1:200-1:1000, Immunohistochemistry: 1:100-1:300, Western Blot: 1:500-1:2000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Granzyme K Polyclonal Antibody. Granzyme K (GrK) belongs to a family of trypsin-like serine proteases localised in the cytotoxic granules of activated T cells and NK cells. It encodes a 28 kDa serine protease whose gene is located on chromosome 5q11-12 close to the granzyme A-encoding gene. Like granzyme A, it has a trypsin-like specifity cleaving at the basic residues arginine and lysine. Granzyme K triggers rapid cell death independently of caspase activation with single-stranded DNA nicks and is primarily expressed in thymus, lung, spleen and peripheral blood leukocytes. |
Immunogen | n/a |
Other Names | GrK |
Gene, Accession # | Entrez: 14945, 29165, 3003; Uniprot: O35205, P49863, P49864 |
Catalog # | PA5-50980 |
Price | |
Order / More Info | Granzyme K Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
产品资料 |
|
|