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| Antigenic Specificity | NAE1 |
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| Clone | OTI1E10 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | NAE1 Monoclonal Antibody (OTI1E10). The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene. |
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| Immunogen | n/a |
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| Other Names | HPP1; ula-1; NAE1; A-116A10.1; NEDD8-activating enzyme E1 regulatory subunit; Amyloid protein-binding protein 1;Amyloid beta precursor protein-binding protein 1, 59 kDa; Proto-oncogene protein 1 |
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| Gene, Accession # | Entrez: 8883; Uniprot: Q13564 |
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| Catalog # | MA5-26665 |
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| Price | |
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| Order / More Info | NAE1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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