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| Product Name | Recombinant Human E3 ubiquitin-protein ligase RAD18 (RAD18) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 72.2kDa. Full Length: 1-495aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). E3 ubiquitin-protein ligase involved in postreplication repair of UV-damaged DNA. Postreplication repair functions in gap-filling of a daughter strand on replication of damaged DNA. Associates to the E2 ubiquitin conjugating enzyme UBE2B to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono-ubiquitination of DNA-associated PCNA on 'Lys-164'. Has ssDNA binding activity. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Postreplication repair protein RAD18; hHR18; hRAD18RING finger protein 73 |
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| Gene, Accession, CAS # | RAD18, UniProt: Q9NS91 |
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| Catalog # | RPC23726 |
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| Order / More Info | Recombinant Human E3 ubiquitin-protein ligase RAD18 (RAD18) from BIOMATIK |
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| Product Specific References | n/a |
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