产品详情 |
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Antigenic Specificity | Phospho-IP3 Receptor 1 (Ser1764) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): 1:50-1:100 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Phospho-IP3 Receptor 1 (Ser1764) Polyclonal Antibody. Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1 (By similarity). Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways. |
Immunogen | n/a |
Other Names | Inositol 1,4,5,-Triphosphate Receptor Type I, IP3R, IP3R1 |
Gene, Accession # | Entrez: 16438, 25262, 3708; Uniprot: P11881, P29994, Q14643 |
Catalog # | PA5-39790 |
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Order / More Info | Phospho-IP3 Receptor 1 (Ser1764) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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