Edit |   |
Antigenic Specificity | SMURF1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 400 µL |
Concentration | n/a |
Applications | Immunohistochemistry: 1:50-1:100, Western Blot: 1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SMURF1 Polyclonal Antibody. SMURF1 is an E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. This protein interacts with receptor-regulated SMADs specific for the BMP pathway, SMAD1 and SMAD5, in order to trigger their ubiquitination and degradation and thereby their inactivation. |
Immunogen | n/a |
Other Names | Smad ubiquitination regulatory factor 1; Ubiquitin--protein ligase SMURF1; Smad-specific E3 ubiquitin ligase 1; hSMURF2 |
Gene, Accession # | Entrez: 57154; Uniprot: Q9HCE7 |
Catalog # | PA5-11944 |
Price | |
Order / More Info | SMURF1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |