| 产品详情 |
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| Antigenic Specificity | SNAIL |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 400 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:10-1:50, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | SNAIL Polyclonal Antibody. Zinc finger protein SNAI1 (SNAIL)is a zinc finger transcriptional repressor which down regulates the expression of the ectodermal gene within the mesoderm and functions to form the mesoderm and neural crest. It is reported that SNAI1 acts as an important factor of tumor invasion as evidenced by its role in E-cadherin down-regulation and induction of epithelial-mesenchymal transition (EMT). In human breast cancer, the expression of SNAI1 and/or the homologous SNAI2 (Slug) has been associated with E-cadherin repression, local or distant metastasis, tumor recurrence, or poor prognosis in different tumor series. It is also reported that Snail 1 protein in the stromamay be anew putative prognosis marker for colon tumor |
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| Immunogen | n/a |
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| Other Names | Zinc finger protein SNAI1, Snail protein homolog, Sna protein |
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| Gene, Accession # | Entrez: 6615; Uniprot: O95863 |
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| Catalog # | PA5-11923 |
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| Price | |
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| Order / More Info | SNAIL Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 25711742, 27341528 |
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