| Edit |   |
|---|
| Antigenic Specificity | Synaptotagmin 1 |
|---|
| Clone | polyclonal |
|---|
| Host Species | Goat |
|---|
| Reactive Species | human |
|---|
| Isotype | n/a |
|---|
| Format | purified |
|---|
| Size | 100 µg |
|---|
| Concentration | n/a |
|---|
| Applications | Immunohistochemistry (Paraffin): 4-6 µg/mL, Immunohistochemistry: 4-6 µg/mL, peptide-ELISA: 1:2000, Western Blot: 0.3-1 µg/mL |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Synaptotagmin 1 Polyclonal Antibody. Synaptotagmin 1 is a synaptic vesicle membrane glycoprotein that is widely expressed throughout the CNS and is generally thought to act as the Ca2+ sensor in the regulation of exocytosis and neurotransmitter release. Studies indicate that synaptotagmin's Ca2+ mediated binding of SNAP25 is essential for the Ca2+ dependent triggering of membrane. It has been demonstrated that discrete residues within the c(2)b binding domain of synaptotagmin 1 independently specify endocytic rate and synaptic vesicle size. Synaptotagmin 1 may have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. Further, Synaptotagmin 1 binds acidic phospholipids with |
|---|
| Immunogen | n/a |
|---|
| Other Names | synaptotagmin I ; DKFZp781D2042; SYT1; P65; SVP65; SYT; synaptotagmin 1 |
|---|
| Gene, Accession # | Entrez: 6857; Uniprot: P21579 |
|---|
| Catalog # | PA5-18856 |
|---|
| Price | |
|---|
| Order / More Info | Synaptotagmin 1 Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|