| 产品详情 |
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| Antigenic Specificity | p38 MAPK alpha |
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| Clone | 6A1 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 2 µg/mL, Immunofluorescence: 2 µg/mL, Western Blot: 3-5 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | p38 MAPK alpha Monoclonal Antibody (6A1). p38 MAPK cascade regulates a variety of cellular responses to stress, inflammation and other signals. p38 MAPK is relatively inactive in the nonphosphorylated form and becomes rapidly activated by dual phosphorylation of a Thr-Gly-Tyr motifs. There are four isoforms of p38 MAPK, which differ in their tissue expression and affinity for upstream activators and downstream effectors. When cells are exposed to tumor necrosis factor, interleukin-1, heat shock, or other activating stimuli, activation of MAPK kinase-3 occurs by phosphorylation. Activated MAPK kinase-3/6 phosphorylate each residue of Thr180 and Tyr182 in p38 MAPK. Phospho-p38 MAPK activates ATF-2, CHOP-1, MEF-2 and other transcription factor |
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| Immunogen | n/a |
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| Other Names | p38-Alpha, p38MAPK, MAPK14, SAPK2A, CSBP1 |
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| Gene, Accession # | Entrez: 1432, 26416, 81649; Uniprot: P47811, P70618, Q16539 |
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| Catalog # | LF-MA0126 |
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| Price | |
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| Order / More Info | p38 MAPK alpha Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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