| 产品详情 |
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| Antigenic Specificity | WRN |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | lyophilized |
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| Applications | Western Blot: 0.5 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | WRN Polyclonal Antibody. This gene encodes a member of the RecQ subfamily and the DEAH (Asp-Glu-Ala-His) subfamily of DNA and RNA helicases. DNA helicases are involved in many aspects of DNA metabolism, including transcription, replication, recombination, and repair. This protein contains a nuclear localization signal in the C-terminus and shows a predominant nucleolar localization. It possesses an intrinsic 3' to 5' DNA helicase activity, and is also a 3' to 5' exonuclease. Based on interactions between this protein and Ku70/80 heterodimer in DNA end processing, this protein may be involved in the repair of double strand DNA breaks. Defects in this gene are the cause of Werner syndrome, an autosomal recessive disorder characterized by prem |
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| Immunogen | n/a |
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| Other Names | Werner syndrome ATP-dependent helicase |
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| Gene, Accession # | Entrez: 290805, 7486; Uniprot: Q14191 |
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| Catalog # | PA5-80232 |
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| Price | |
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| Order / More Info | WRN Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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