Edit |   |
Antigenic Specificity | ACE2 |
Clone | OTI4D2 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:200 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ACE2 Monoclonal Antibody (OTI4D2). ACE2 cDNA encodes a deduced 805-amino acid protein containing a potential 17-amino acid N-terminal signal peptide and a putative 22-amino acid C-terminal membrane anchor. It also possesses a zinc metalloprotease consensus sequence and a conserved glutamine residue that may function as a third zinc ligand. ACE2 is expressed predominantly in vascular endothelial cells of the heart and kidney. ACE converts angiotensin I to angiotensin II, ACE2 converts angiotensin I to angiotensin 1-9, which has 9 amino acids. Angiotensin II is a potent blood vessel constrictor, while angiotensin 1-9 does not impact blood vessels but is cleaved by ACE to a shorter peptide, angiotensin 1-7, which is a blood vessel dilator. Spi |
Immunogen | n/a |
Other Names | Angiotensin-converting enzyme 2; ACE-related carboxypeptidase; Angiotensin-converting enzyme homolog; ACEH; Metalloprotease MPROT15; Processed angiotensin-converting enzyme 2; ACE 2; ORF Names: UNQ868/PRO1885 |
Gene, Accession # | Entrez: 59272; Uniprot: Q9BYF1 |
Catalog # | MA5-26628 |
Price | |
Order / More Info | ACE2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |