| 产品详情 |
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| Antigenic Specificity | p107 Ser975 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | Protein A purified |
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| Size | 100ul |
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| Concentration | 1ug/ul |
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| Applications | WB, IHC-P, IF(IHC-P) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | p107(Ser975) Polyclonal Antibody. • Target Background: Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibito |
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| Immunogen | KLH conjugated synthetic phosphopeptide derived from human RBL1 around the phosphorylation site of Ser975. Immunogen Range: 950-1000/1068 |
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| Other Names | Phosphorylated, phospho-PRB1; p107; CP107; Retinoblastoma-like protein 1; 107 kDa retinoblastoma-associated protein; RBL1 |
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| Gene, Accession # | Gene ID: 5933, SwissProt: P28749 |
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| Catalog # | bs-5696R |
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| Price | |
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| Order / More Info | p107 Ser975 Antibody from BIOSS ANTIBODIES |
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| Product Specific References | Wang et al. (2016) Mol.Med.Rep. 14:1309-15. PubMed: 27279047 |
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