Edit |   |
Antigenic Specificity | C1orf86 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL, Immunohistochemistry: 1:50-1:200, Western Blot: 0.4 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | C1orf86 Polyclonal Antibody. C1orf86 is a component of the Fanconi anemia (FA) complex required to recruit the FA complex to DNA interstrand cross-links (ICLs) and promote ICLs repair. Following DNA damage recognizes and binds 'Lys-63'-linked ubiquitin generated by RNF8 at ICLs and recruits other components of the FA complex. It promotes translesion synthesis via interaction with REV1. |
Immunogen | n/a |
Other Names | Fanconi anemia core complex associated protein 20, FP7162 |
Gene, Accession # | Entrez: 199990; Uniprot: Q6NZ36 |
Catalog # | PA5-58555 |
Price | |
Order / More Info | C1orf86 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |