| 产品详情 |
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| Antigenic Specificity | KCNQ3 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 2 µg/mL, Immunofluorescence: 2 µg/mL, Immunohistochemistry (Frozen): 0.5 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | KCNQ3 Polyclonal Antibody. KCNQs are members of the voltage-dependent non-inactivating potassium channel family. Currently there are five known KCNQs (KCNQ1-5) found in the central nervous system and KCNQ2 and 3 have demonstrated their importance in M-current activation. Studies have shown that KCNQ2 and KCNQ3 form heteromultimers that, when formed, substantially increase the M-current. Inhibition of M-current controls neuron excitability throughout the nervous system as well as the responsiveness to synaptic inputs. Genetic mutations in these proteins have been linked to disorders such as benign familial neonatal convulsions (BFNC), deafness, neuropathic pain and epilepsy. |
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| Immunogen | n/a |
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| Other Names | BFNC, BFNC2, EBN2, Voltage-gated potassium channel subunit Kv7.3 |
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| Gene, Accession # | Entrez: 110862, 29682, 3786; Uniprot: O43525, O88944, Q8K3F6 |
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| Catalog # | PA1-930 |
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| Price | |
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| Order / More Info | KCNQ3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 12466226 |
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