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Antigenic Specificity | 4-1BB Ligand |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | 4-1BB Ligand Polyclonal Antibody. The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required |
Immunogen | n/a |
Other Names | TNFSF9; CDw137L; CD137L; 4-1BBL; 41BBL |
Gene, Accession # | Entrez: 8744; Uniprot: P41273 |
Catalog # | PA5-66287 |
Price | |
Order / More Info | 4-1BB Ligand Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |