| 产品详情 |
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| Antigenic Specificity | MLH1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunoprecipitation: 1-4 µg/mg lysate, Western Blot: 1:500-1:5,000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MLH1 Polyclonal Antibody. MLH1 is a DNA mismatch repair protein. The repair of mismatch DNA is essential to maintaining the integrity of genetic information over time. An alteration of microsatellite repeats is the result of slippage owing to strand misalignment during DNA replication and is referred to as microsatellite instability (MSI). These defects in DNA repair pathways have been related to human carcinogenesis. The importance of mismatch repair genes became apparent with the identification of the genetic basis for hereditary nonpolyposis colon cancer (HNPC). MSHS2 is involved in the initial cognition of mismatch nucleotides during the replication mismatch repair process. It is thought that after MSH2 binds to a mismatched DNA duplex |
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| Immunogen | n/a |
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| Other Names | COCA2, FCC2, HNPCC, HNPCC2, MGC5172, hMLH1 |
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| Gene, Accession # | Entrez: 4292; Uniprot: P40692 |
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| Catalog # | A300-015A |
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| Price | |
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| Order / More Info | MLH1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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