| 产品详情 |
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| Antigenic Specificity | Ricin alpha |
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| Clone | RA999 |
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| Host Species | Mouse |
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| Reactive Species | plant |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 200 µg |
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| Concentration | n/a |
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| Applications | ELISA: Assay Dependent, Western Blot: Assay Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Ricin alpha Monoclonal Antibody (RA999). Ricin toxin (RCA60), is a 60 kDa glycoprotein that consists of two chains, A and B, covalently linked by disulfide bond. The A chain acts as a glycosidase that removes an adenine residue from the 28S rRNA. The area from which the adenine is removed is essental for binding of elongation factors, destroying it leaves the ribosome inactive and unable to support protein synthesis. The A chain can inactivate a few thousand ribosomes per minute, much faster than the cell can replace them, meaning that a single ricin A chain can kill a cell. The B chain binds to complex carbohydrates on the cell surface to facilitate entry of the A Chain into the cell. Without the B chain, the A chain has very low toxicity. |
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| Immunogen | n/a |
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| Other Names | n/a |
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| Gene, Accession # | Entrez: 8287993; Uniprot: P02879 |
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| Catalog # | MA1-74225 |
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| Price | |
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| Order / More Info | Ricin alpha Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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