产品详情 |
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Antigenic Specificity | NRXN3 |
Clone | polyclonal |
Host Species | Sheep |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | lyophilized |
Applications | Immunohistochemistry: 5-15 µg/mL, Western Blot: 1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NRXN3 Polyclonal Antibody. Neurexins comprise a family of neuronal cell surface proteins, which include neurexin I (NRXN1), neurexin II (NRXN2), neurexin III (NRXN3) and Caspr (neurexin IV). Neurexins I-III are expressed as a and b isoforms. The a isoforms are made of three cassettes, which contain two LNS (Laminin A, Neurexins, Sex hormone-binding)-domains separated by EGF domains, followed by a transmembrane region and a 55 amino acid cytoplasmic C-terminal. The a isoforms bind to neurexophilins at the second LNS site and to the excitatory neurotoxin a-latrotoxin. The b isoforms have only one LNS-domain, bind to neuroligins, and play a role in the formation and remodeling of synapes. Caspr (for Contactin-Associated Protein 1, also designa |
Immunogen | n/a |
Other Names | Neurexin-3, Neurexin III-alpha, Neurexin-3-alpha, NRXN3, C14orf60, KIAA0743 |
Gene, Accession # | Entrez: 18191, 9369; Uniprot: Q6P9K9, Q9HDB5 |
Catalog # | PA5-47714 |
Price | |
Order / More Info | NRXN3 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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