| 产品详情 |
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| Antigenic Specificity | CD11a |
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| Clone | 8-6.2 |
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| Host Species | Mouse |
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| Reactive Species | mouse |
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| Isotype | IgG2a |
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| Format | fluorescein (FITC) conjugate |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 1.0 µg/1x10^6 cells |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD11a Monoclonal Antibody (8-6.2), FITC. CD11a (LFA-1 alpha, ITGAL) together with CD18 constitute leukocyte function-associated antigen 1 (LFA-1), the alphaLbeta2 integrin. CD11a is implicated in activation of LFA-1 complex. CD11a plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. CD11a is expressed on the plasma membrane of leukocytes in a low-affinity conformation. Cell stimulation by chemokines or other signals leads to induction the high-affinity conformation, which supports tight binding of CD11a to its ligands, the intercellular adhesion molecules ICAM-1, -2, -3. CD11a is thus |
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| Immunogen | n/a |
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| Other Names | CD11 antigen-like family member A, LFA-1 alpha, LFA-1A, antigen CD11A p180, lymphocyte function-associated antigen 1 alpha polypeptide, integrin alpha-L |
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| Gene, Accession # | Entrez: 16408; Uniprot: P24063 |
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| Catalog # | MA5-17795 |
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| Price | |
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| Order / More Info | CD11a Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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