| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | CD11a |
|---|
| Clone | MEM-83 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG1 |
|---|
| Format | purified |
|---|
| Size | 100 µg |
|---|
| Concentration | n/a |
|---|
| Applications | Flow Cytometry: Assay Dependent, Functional Assay: Assay-Dependent, Immunoprecipitation: Assay Dependent |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | CD11a Monoclonal Antibody (MEM-83). CD11a (LFA-1 alpha, ITGAL) together with CD18 constitute leukocyte function-associated antigen 1 (LFA-1), the alphaLbeta2 integrin. CD11a is implicated in activation of LFA-1 complex. CD11a plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. CD11a is expressed on the plasma membrane of leukocytes in a low-affinity conformation. Cell stimulation by chemokines or other signals leads to induction the high-affinity conformation, which supports tight binding of CD11a to its ligands, the intercellular adhesion molecules ICAM-1, -2, -3. CD11a is thus invo |
|---|
| Immunogen | n/a |
|---|
| Other Names | CD11 antigen-like family member A, LFA-1 alpha, LFA-1A, antigen CD11A p180, lymphocyte function-associated antigen 1 alpha polypeptide, integrin alpha-L |
|---|
| Gene, Accession # | Entrez: 3683; Uniprot: P20701 |
|---|
| Catalog # | MA1-19021 |
|---|
| Price | |
|---|
| Order / More Info | CD11a Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | PubMed: 22970312 |
|---|
| 产品资料 |
|
|