| 产品详情 |
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| Antigenic Specificity | CD11a |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | lyophilized |
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| Applications | Flow Cytometry: Assay-dependent, Immunocytochemistry: Assay-dependent, Immunohistochemistry (Paraffin): 1 µg/mL, Western Blot: 0.5 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD11a Polyclonal Antibody. CD11a (LFA-1 alpha, ITGAL) together with CD18 constitute leukocyte function-associated antigen 1 (LFA-1), the alphaLbeta2 integrin. CD11a is implicated in activation of LFA-1 complex. CD11a plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. CD11a is expressed on the plasma membrane of leukocytes in a low-affinity conformation. Cell stimulation by chemokines or other signals leads to induction the high-affinity conformation, which supports tight binding of CD11a to its ligands, the intercellular adhesion molecules ICAM-1, -2, -3. CD11a is thus involved in i |
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| Immunogen | n/a |
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| Other Names | Integrin alpha-L, CD11 antigen-like family member A, Leukocyte adhesion glycoprotein LFA-1 alpha chain, LFA-1A, Leukocyte function-associated molecule 1 alpha chain, CD11a, ITGAL, CD11A |
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| Gene, Accession # | Entrez: 3683; Uniprot: P20701 |
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| Catalog # | PA5-79531 |
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| Price | |
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| Order / More Info | CD11a Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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