产品详情 |
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Antigenic Specificity | CD1a |
Clone | O10 |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1, kappa |
Format | purified |
Size | 500 µL |
Concentration | n/a |
Applications | Flow Cytometry: 2 µg/test, Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:100-1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD1a Monoclonal Antibody (O10). CD1a is a non-polymorphic MHC Class 1 related cell surface glycoprotein, expressed in association with Beta 2 microglobulin. CD1a is expressed by cortical thymocytes, Langerhan's cells and by interdigitating cells. CD1a is also expressed by some malignancies of T cell lineage and in histiocytosis X. CD1a is expressed on cortical thymocytes, epidermal Langerhans cells, dendritic cells, on certain T-cell leukemias, and in various other tissues. CD1a is structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human gen |
Immunogen | n/a |
Other Names | CD1, FCB6, HTA1, R4, T6, CD1A antigen, a polypeptide, T-cell surface antigen T6/Leu-6, T-cell surface glycoprotein CD1a, cluster of differentiation 1 A, cortical thymocyte antigen CD1A |
Gene, Accession # | Entrez: 909; Uniprot: P06126 |
Catalog # | MA5-12526 |
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Order / More Info | CD1a Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 16622033, 18780835, 18995203, 19258510, 19909745, 20955708, 22720025, 23331470, 24767700, 26172445, 26392518, 26893647 |
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