产品详情 |
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Antigenic Specificity | CD300a |
Clone | MEM-260 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Flow Cytometry: 2 µg/mL, Western Blot: Assay Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD300a Monoclonal Antibody (MEM-260). CD300a (CMRF-35H, IRp60) is a non-MHC-specific inhibitory receptor of immunoglobulin superfamily, which contains three immunoreceptor tyrosine-based inhibitory motifs (ITIMs) that associate with SH2-containing phosphatases SHP-1 and SHP-2. CD300a is expressed on many cell types including T cells, NK cells, neutrophils, eosinophils or mast cells. Its triggering inhibits activating signals such as those of IL5, GM-CSF or eotaxin, as well as supresses mast cell degranulation or NK cell cytotoxic activity. |
Immunogen | n/a |
Other Names | CLM-8, CMRF-35-H9, CMRF-35H, CMRF35-H, CMRF35-H9, CMRF35H, CMRF35H9, IGSF12, IRC1, IRC1/IRC2, IRC2, IRp60, CD300 antigen-like family member A, CD300a antigen, CMRF35-like molecule 8, IGSF12 |
Gene, Accession # | Entrez: 11314; Uniprot: Q9UGN4 |
Catalog # | MA1-10190 |
Price | |
Order / More Info | CD300a Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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