| 产品详情 |
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| Antigenic Specificity | E2F6 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | ChIP assay: 1:50-1:200, Immunocytochemistry: 1:50-1:200, Immunofluorescence: 1:50-1:200, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | E2F6 Polyclonal Antibody. The human retinoblastoma gene product appears to play an important role in the negative regulation of cell proliferation. Functional inactivation of Rb can be mediated either through mutation or as a consequence of interaction with DNA tumor virus encoded proteins. Of all the Rb associations described to date, the identification of a complex between Rb and the transcription factor E2F most directly implicates Rb in regulation of cell proliferation. E2F was originally identified through its role in transcriptional activation of the adenovirus E2 promoter. Sequences homologous to the E2F binding site have been found upstream of a number of genes that encode proteins with putative functions in the G1 and S phases of t |
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| Immunogen | n/a |
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| Other Names | Transcription factor E2F6; E2F-6; E2F6 |
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| Gene, Accession # | Entrez: 1876, 50496; Uniprot: O54917, O75461 |
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| Catalog # | PA5-77033 |
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| Price | |
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| Order / More Info | E2F6 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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