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Antigenic Specificity | NuMA |
Clone | GT1510 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Western Blot: 1:500-1:3000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NuMA Monoclonal Antibody (GT1510). Highly abundant component of the nuclear matrix where it may serve a non-mitotic structural role, occupies the majority if the nuclear volume. Required for maintenance and establishment of the mitotic spindle poles, functionning as a tether linking bulk microtubules of the spindle to centrosomes. May be involved in coordination of the alignment of the mitotic spindle to the cellular polarity axis, which is a prerequisite for asymmetric cell divisions. |
Immunogen | n/a |
Other Names | SP-H antigen, centrophilin stabilizes mitotic spindle in mitotic cells, structural nuclear protein |
Gene, Accession # | Entrez: 4926; Uniprot: Q14980 |
Catalog # | MA5-17286 |
Price | |
Order / More Info | NuMA Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |