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| Antigenic Specificity | NUMB |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunoprecipitation: 2-5 µg/mg lysate |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | NUMB Polyclonal Antibody. ProteinNUMB homolog is an evolutionarily conserved protein that controls the differentiation of neuronal progenitor cells. Recent studies have revealed that NUMB functions in clathrin-dependent endocytosis by binding to the AP-2 complex. NUMB is also expressed in postmitotic neurons and plays a role in axonal growth. Neural cells expressing Numb isoforms with short phosphotyrosine-binding (SPTB) domain undergo extensive neurite outgrowth, an effect that can be blocked by voltage-gated Ca2+ channel (VGCC) inhibitor or by Ca2+ chelator. |
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| Immunogen | n/a |
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| Other Names | Protein S171 |
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| Gene, Accession # | Entrez: 8650; Uniprot: P49757 |
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| Catalog # | A301-715A |
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| Price | |
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| Order / More Info | NUMB Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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