| 产品详情 |
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| Antigenic Specificity | Kir3.4 (KCNJ5) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 1:500-1:1000, Western Blot: 0.4 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Kir3.4 (KCNJ5) Polyclonal Antibody. G protein-coupled inwardly rectifying potassium channels (Kir3.1 through Kir3.4) are coupled to numerous neurotransmitter receptors in the brain and are abundantly expressed in the olfactory bulb, hippocampus, neocortex, dentate gyrus, cerebellar cortex and thalamus regions of the brain. Also known as GIRK, Kir3 potassium channels localize to the soma and dendrites as well as axons of neurons. Liberated Gbg subunits from G protein heterotrimers bind to and regulate Kir3 channel activity. Gb3- and Gb4-containing Gbg dimers bind directly to cytoplasmic domains of Kir3 proteins and increase the K+ current while Gb5-containing Gbg dimers inhibit Kir3 K+ current. Kir3 activity is also inhibited by tyrosine pho |
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| Immunogen | n/a |
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| Other Names | G protein-activated inward rectifier potassium channel 4, GIRK-4, GIRK4, Cardiac inward rectifier, CIR, Heart KATP channel, Inward rectifier K(+) channel Kir3.4, IRK-4, KATP-1, IRK4, KATP1, Potassium channel, inwardly rectifying subfamily J member 5, KCNJ5 |
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| Gene, Accession # | Entrez: 3762; Uniprot: P48544 |
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| Catalog # | PA5-53222 |
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| Price | |
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| Order / More Info | Kir3.4 (KCNJ5) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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